Research programme: antivirals - Microbiotix

Drug Profile

Research programme: antivirals - Microbiotix

Alternative Names: MBX 468; MBX 685; MBX 769S

Latest Information Update: 26 Sep 2012

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At a glance

  • Originator Microbiotix
  • Developer Microbiotix; University of Michigan
  • Class Cyclopropanes; Purine nucleosides; Small molecules
  • Mechanism of Action Nucleoside reverse transcriptase inhibitors; Virus internalisation inhibitors; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cytomegalovirus infections; Hepatitis C; Herpesvirus infections; Influenza A virus H5N1 subtype
  • Discontinued Epstein-Barr virus infections; Hepatitis B

Most Recent Events

  • 26 Sep 2012 Preclinical development is ongoing in USA
  • 01 May 2012 Microbiotix receives Phase II SBIR grant from National Institute of Allergy and Infectious Diseases for methylenecyclopropane analogues development in Herpesvirus infections
  • 16 Sep 2011 Microbiotix initiates clinical development of its lead methylenecyclopropane candidate, cyclopropavir
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