Research programme: Rho GTP-binding protein inhibitors - ExonHit Therapeutics

Drug Profile

Research programme: Rho GTP-binding protein inhibitors - ExonHit Therapeutics

Alternative Names: EHT 0101; EHT 0206; EHT 101; EHT 1864; EHT 206

Latest Information Update: 04 Jul 2013

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At a glance

  • Originator ExonHit Therapeutics
  • Developer Diaxonhit
  • Class Small molecules
  • Mechanism of Action Amyloid beta-protein inhibitors; GTP phosphohydrolase inhibitors; Ras signal transduction pathway inhibitors; Rho GTP-binding protein-inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Preclinical Alzheimer's disease; Cancer; Chronic myeloid leukaemia

Most Recent Events

  • 19 Dec 2012 ExonHit Therapeutics has merged with InGen Biosciences to form Diaxonhit
  • 19 Nov 2009 Pharmacodynamics data from preclinical trials in Cancer presented at the 21st AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2009)
  • 04 Sep 2008 Preclinical trials in Cancer in France (unspecified route)
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