Tenofovir alafenamide

Drug Profile

Tenofovir alafenamide

Alternative Names: GS-7340; GS-7340-02; GS-7340-03; TAF; Tenofovir alafenamide fumarate; Vemlidy

Latest Information Update: 18 Sep 2017

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At a glance

  • Originator Gilead Sciences
  • Developer Gilead Sciences; University Hospital Inselspital
  • Class Antiretrovirals; Purines; Small molecules
  • Mechanism of Action Nucleotide reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hepatitis B
  • Phase III HIV-1 infections
  • Phase II HIV infections

Most Recent Events

  • 09 Aug 2017 Launched for Hepatitis B (Treatment-naive, Treatment-experienced) in USA before August 2017 (PO)
  • 31 Jul 2017 Gilead Sciences completes a phase III trial in HIV-1 infections (Treatment experienced) in Uganda, Thailand, Dominican Republic, Russia, United Kingdom, Germany, USA (PO) (EudraCT2013-002830-19) (NCT01967940)
  • 29 Jun 2017 Gilead Sciences initiates enrolment in a phase II trial for Hepatitis B (Treatment-experienced) in USA (PO, Tablet) (NCT03180619)
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