Drug Profile


Alternative Names: '162; 353162; Bupropion metabolite; GW 353162

Latest Information Update: 21 Jan 2008

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At a glance

  • Originator GlaxoSmithKline
  • Class Antidepressants; Anxiolytics; Propiophenones; Small molecules
  • Mechanism of Action Adrenergic receptor antagonists; Dopamine uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Bipolar disorders; Fibromyalgia; Major depressive disorder; Neuropathic pain; Obesity; Restless legs syndrome

Most Recent Events

  • 03 Aug 2006 Discontinued - Phase-II for Depression in United Kingdom (unspecified route)
  • 06 Dec 2005 Phase-I clinical trials in Obesity in United Kingdom (unspecified route)
  • 22 Apr 2005 Phase-I clinical trials in Neuropathic pain in United Kingdom (unspecified route)
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