Drug Profile


Alternative Names: R-1439; RG1439; RO-0728804

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Roche
  • Class Antihyperglycaemics; Oxazoles; Propionic acids; Small molecules; Thiophenes
  • Mechanism of Action Peroxisome proliferator-activated receptor alpha agonists; Peroxisome proliferator-activated receptor gamma agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cardiovascular disorders; Type 2 diabetes mellitus

Most Recent Events

  • 17 Jul 2013 Biomarkers information updated
  • 10 Jul 2013 Discontinued - Phase-I for Cardiovascular disorders (in volunteers, prevention) in China (PO)
  • 10 Jul 2013 Discontinued - Phase-II for Type-2 diabetes mellitus (combination therapy, treatment-experienced) in Germany (PO)
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