Drug Profile


Alternative Names: Albugon; Albumin-GLP-1 fusion protein; Albumin-glucagon-like peptide-1 fusion protein; Eperzan; GLP-1-albumin fusion protein; Glucagon-like peptide-1-albumin fusion protein; GSK 716155; Syncria®; Tanzeum

Latest Information Update: 03 Oct 2017

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At a glance

  • Originator Human Genome Sciences
  • Developer GlaxoSmithKline
  • Class Albumins; Antihyperglycaemics; Glucagon-like peptides; Obesity therapies; Recombinant fusion proteins
  • Mechanism of Action Glucagon like peptide 1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Type 2 diabetes mellitus
  • Phase II Type 1 diabetes mellitus
  • Discontinued Heart failure

Most Recent Events

  • 14 Sep 2017 GlaxoSmithKline withdraws a phase III trial for Type-2 diabetes mellitus (In children, In adolescents) as the asset will be withdrawn from the market prior to study end in USA (SC) (NCT03015519)
  • 24 Jul 2017 GlaxoSmithKline completes a phase III trial for Type-2 diabetes mellitus in Denmark, Hungary, USA, Brazil, Canada, France, Germany, Italy, South Korea, Mexico, Philippines, Poland, South Africa, United Kingdom and Spain (NCT02229227)
  • 23 May 2017 GlaxoSmithKline completes a phase III trial for Type-2 diabetes mellitus (Adjunctive treatment) in USA (SC) (NCT02683746)
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