X4P 001

Drug Profile

X4P 001

Alternative Names: AMD-070; AMD11070; X4P001

Latest Information Update: 02 Jan 2017

Price : $50

At a glance

  • Originator AnorMED
  • Developer X4 Pharmaceuticals
  • Class Antineoplastics; Small molecules
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Immunodeficiency disorders
  • Phase I/II Renal cell carcinoma
  • Phase I Malignant melanoma; Solid tumours
  • Discontinued HIV-1 infections

Most Recent Events

  • 01 Dec 2016 Phase-II/III clinical trials in Immunodeficiency disorders (WHIM Syndrome; In adolescents, In adults) in USA (PO) (NCT03005327)
  • 30 Nov 2016 Pharmacodynamics data from a preclinical study in Renal cell carcinoma presented at the EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium (EORTC-NCI-AACR 2016)
  • 01 Oct 2016 Phase-I/II clinical trials in Renal cell carcinoma (Late-stage disease, Adjunctive treatment) in USA (PO) (NCT02923531)
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