Research programme: motor neuron disease gene therapy - Oxford BioMedica

Drug Profile

Research programme: motor neuron disease gene therapy - Oxford BioMedica

Alternative Names: Amyotrophic lateral sclerosis gene therapy - Oxford BioMedica; MoNuDin; OXB-103; SMN-1G; Spinal muscular atrophy gene therapy - Oxford BioMedica

Latest Information Update: 25 Jan 2011

Price : $50

At a glance

  • Originator Oxford BioMedica; The Cleveland Clinic Foundation
  • Developer Katholieke Universiteit Leuven; Oxford BioMedica; VIB
  • Class Gene therapies; Spinal muscular atrophy gene therapies
  • Mechanism of Action Angiogenesis modulating agents; Gene transference; Genetic transcription stimulants; Survival of motor neuron 1 protein expression stimulants; Vascular endothelial growth factor A expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity No
  • Available For Licensing Yes - Amyotrophic lateral sclerosis; Motor neuron disease

Highest Development Phases

  • Preclinical Amyotrophic lateral sclerosis; Motor neuron disease; Spinal muscular atrophy

Most Recent Events

  • 25 Jan 2011 Preclinical development is ongoing in United Kingdom
  • 25 Jan 2011 Oxford BioMedica's motor neuron disease gene therapy is still available for licensing http://www.oxfordbiomedica.co.uk/
  • 01 Jul 2010 Preclinical trials in Amyotrophic lateral sclerosis in Belgium (IM)
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