Teriflunomide - Sanofi Genzyme

Drug Profile

Teriflunomide - Sanofi Genzyme

Alternative Names: A-77-1726; Aubagio; AVE-1726; HMR-1726; HMR1726D; RS-61980; SU-0020

Latest Information Update: 13 Dec 2017

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At a glance

  • Originator sanofi-aventis
  • Developer Genzyme Corporation; Sanofi; Sanofi Genzyme
  • Class Antirheumatics; Hydroxybutyrates; Nitriles; Small molecules; Toluidines
  • Mechanism of Action Dihydroorotate dehydrogenase inhibitors; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Multiple sclerosis

Most Recent Events

  • 25 Oct 2017 Efficacy data from a phase II extension trial in Multiple sclerosis presented at the 7th joint ECTRIMS-ACTRIMS meeting (ECTRIMS-ACTRIMS-2017)
  • 25 Sep 2017 Sanofi initiates enrolment in the phase III TERIS trial for Multiple sclerosis in France (PO) (NCT03122652)
  • 25 Apr 2017 Efficacy and adverse events data from an extension of the phase III TOPIC trial in Multiple sclerosis released by Sanofi Genzyme
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