IMO 2055

Drug Profile

IMO 2055

Alternative Names: EMD 1201081; HYB-2055; IMO-2055; IMOxine; TLR9 immunomodulator

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Idera Pharmaceuticals
  • Developer Idera Pharmaceuticals; Merck KGaA
  • Class Antineoplastics; Oligonucleotides
  • Mechanism of Action Toll-like receptor 9 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Colorectal cancer; Head and neck cancer; Non-small cell lung cancer

Highest Development Phases

  • Preclinical Cancer
  • Suspended Colorectal cancer; Non-small cell lung cancer
  • No development reported Head and neck cancer
  • Discontinued Asthma; Renal cell carcinoma

Most Recent Events

  • 04 Aug 2015 No recent reports on development identified - Phase-II for Head and neck cancer (Combination therapy, Metastatic disease, Recurrent, Second-line therapy or greater) in USA, Belgium, Czech Republic, France, Hungary, United Kingdom, Slovakia and Poland (SC)
  • 02 Dec 2014 Final pharmacodynamics data from preclinical models of bladder, colon, and lung cancer released by Idera Pharmaceuticals
  • 01 Jun 2014 Preclinical trials in Cancer in USA (Intratumoural)
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