Drug Profile


Alternative Names: AZD 0530; Saracatinib difumarate

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; Baylor College of Medicine; Brigham and Women's Hospital; Loyola University Chicago; NHS National Services Scotland; Sheffield Teaching Hospitals NHS Foundation Trust; Stanford University; University of Cincinnati; University of Miami; University of South Florida; Yale University
  • Class Analgesics; Antidementias; Antineoplastics; Benzodioxoles; Quinazolines; Small molecules
  • Mechanism of Action Src-Family kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Cancer pain; Lymphangioleiomyomatosis
  • Phase I Alcoholism
  • Discontinued Bone cancer; Breast cancer; Ovarian cancer; Prostate cancer; Solid tumours

Most Recent Events

  • 31 Jul 2017 Sheffield Teaching Hospitals NHS Foundation Trust and AstraZeneca completes a phase II trial in Cancer pain (In adolescents, In adults, In the elderly) in United Kingdom (NCT02085603)
  • 31 Mar 2017 AstraZeneca completes a phase II trial in Breast cancer (Combination therapy, Late-stage disease) in United Kingdom (PO) (ISRCTN23804370)
  • 03 Nov 2016 Yale University plans a phase II trial for Alcoholism (In volunteers) in USA (PO) (NCT02955186)
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