AEG 35156

Drug Profile

AEG 35156

Alternative Names: AEG 161; AEG35156; GEM 640

Latest Information Update: 29 Jul 2015

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At a glance

  • Originator Idera Pharmaceuticals
  • Developer Aegera Therapeutics
  • Class Antineoplastics; Antisense oligonucleotides
  • Mechanism of Action X-linked inhibitor of apoptosis protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; B cell lymphoma; Breast cancer; Chronic lymphocytic leukaemia; Hepatocellular carcinoma; Multiple sclerosis; Non-small cell lung cancer; Pancreatic cancer

Most Recent Events

  • 12 Jul 2011 Aegera Therapeutics terminates phase I/II trial in Chronic lymphocytic leukaemia and B-cell lymphoma in USA and Canada NCT00768339)
  • 27 May 2011 Aegera Therapeutics has been acquired by Pharmascience
  • 19 Jul 2010 Efficacy and adverse events data from a phase I/II trial in Hepatocellular carcinoma released by Aegera Therapeutics
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