Lintuzumab Ac-225

Drug Profile

Lintuzumab Ac-225

Alternative Names: 225Ac-HuM-195; 225Ac-lintuzumab; AC225 MOAB M195; Ac225 monoclonal antibody M195; Actimab-A; Actimab-M; Actinium-225 (225Ac)-Lintuzumab; Actinium-225-labelled HuM195; HuM195-Ac-225

Latest Information Update: 11 Jul 2017

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At a glance

  • Originator PDL BioPharma
  • Developer Actinium Pharmaceuticals; Baylor Research Institute; Memorial Sloan-Kettering Cancer Center; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Immunoconjugates; Monoclonal antibodies; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • New Molecular Entity No
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Phase I Multiple myeloma

Most Recent Events

  • 06 Jul 2017 Actinum Pharmaceuicals expects to complete enrolment in phase II part of a phase I/II trial for Acute myeloid leukaemia (First-line therapy, Newly diagnosed, In the elderly) in USA and Puerto Rico in the first half of 2018
  • 15 Jun 2017 Lintuzumab Ac-225 is available for licensing as at 15 June 2017
  • 24 May 2017 Lintuzumab Ac-225 receives Orphan Drug status for Acute myeloid leukaemia (First-line therapy, In the elderly) in European Union
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