Ofatumumab

Drug Profile

Ofatumumab

Alternative Names: Anti-CD20 monoclonal antibody - Novartis; Arzerra; GSK-1841157; HuMax CD20; OMB-157

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator Genmab
  • Developer Genmab; GlaxoSmithKline; Mundipharma International; National Cancer Centre (Singapore); Novartis; Roswell Park Cancer Institute; University Health Network
  • Class Antineoplastics; Antirheumatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action CD20 antigen inhibitors; Immunosuppressants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic lymphocytic leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Chronic lymphocytic leukaemia
  • Phase III Diffuse large B cell lymphoma; Follicular lymphoma; Multiple sclerosis
  • Phase II Acute lymphoblastic leukaemia; MALT lymphoma
  • Suspended Neuromyelitis optica
  • Discontinued Pemphigus vulgaris; Rheumatoid arthritis; Waldenstrom's macroglobulinaemia

Most Recent Events

  • 05 Apr 2017 Novartis plans regulatory filings in relapsing Multiple sclerosis in 2019
  • 31 Mar 2017 GlaxoSmithKline completes a phase II trial for Non-Hodgkin's Lymphoma (Second-line or greater therapy) in the US (NCT01294579)
  • 28 Jan 2017 GlaxoSmithKline completes a phase-II trial in MALT lymphoma (Combination therapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Italy (IV) (EudraCT2011-003495-36)
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