Drug Profile


Alternative Names: Anti-CCR2 monoclonal antibody; MLN-1202; TAK-202

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Millennium Pharmaceuticals
  • Developer Millennium; Millennium Pharmaceuticals; Takeda; Takeda Oncology
  • Class Anti-inflammatories; Antirheumatics; Monoclonal antibodies
  • Mechanism of Action CCR2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atherosclerosis; Diabetic nephropathies
  • Phase I Malignant melanoma
  • Discontinued Multiple sclerosis; Rheumatoid arthritis; Scleroderma

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 01 Oct 2016 Takeda withdraws a phase I trial in Healthy volunteers prior to enrollment in Japan due to a business decision and no safety or efficacy concerns (NCT02426021)
  • 26 Jul 2016 Takeda terminates phase I trial in Healthy volunteers in Japan (NCT02426021)
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