Eltrombopag

Drug Profile

Eltrombopag

Alternative Names: 497115; Eltrombopag olamine; Promacta; Revolade; SB-497115; SB-497115-GR

Latest Information Update: 19 Jan 2017

Price : $50

At a glance

  • Originator Ligand Pharmaceuticals
  • Developer GlaxoSmithKline; Novartis; Technische Universitat Dresden
  • Class Benzoates; Hydrazines; Pyrazoles; Small molecules
  • Mechanism of Action Thrombopoietin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic thrombocytopenic purpura
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Aplastic anaemia; Idiopathic thrombocytopenic purpura; Thrombocytopenia
  • Phase II Acute myeloid leukaemia

Most Recent Events

  • 16 Dec 2016 Novartis Pharmaceuticals plans the phase II SOAR trial for Aplastic anaemia (Combination therapy, Treatment-naive, In children, In adolescents, In adults) in Brazil, France and Spain (PO, Tablet) (NCT02998645)
  • 09 Dec 2016 Scottish Medicines Consortium (SMC) approves eltrombopag for restricted use within NHS Scotland for the treatment of chronic idiopathic thrombocytopenic purpura
  • 06 Dec 2016 Efficacy data from a phase I/II trial in Acute myeloid leukemia presented at the 58th Annual Meeting and Exposition of the American Society of Hematology
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top