Drug Profile


Alternative Names: AEZS-130; ARD-07; D-87575; EP-01572; EP-1572; JMV-1843; Macimorelin acetate; Macrilen; Solorel

Latest Information Update: 09 Mar 2017

Price : $50

At a glance

  • Originator AEterna Zentaris Inc
  • Class Amides; Carboxylic acids; Indoles; Oligopeptides; Small molecules
  • Mechanism of Action Ghrelin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Somatotropin deficiency
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preregistration Somatotropin deficiency
  • Phase II Cachexia

Most Recent Events

  • 09 Mar 2017 The Pediatric Committee of the European Medicines Agency agrees to Aeterna Zentaris to postpone its Pediatric Investigation Plan (PIP) until it files an MAA for Macimorelin for the treatment of somatotropin-deficiency in adults
  • 07 Mar 2017 The Pediatric Committee of the European Medicines Agency accepts Aeterna Zentaris's Pediatric Investigation Plan for Macimorelin
  • 01 Nov 2016 Aeterna Zentaris completes phase III trial in Somatotropin deficiency (Diagnosis, In adults) in USA, Austria, France, Germany, Italy, Poland, Serbia, Spain, and the UK (NCT02558829)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top