Capsaicin - Centrexion Therapeutics

Drug Profile

Capsaicin - Centrexion Therapeutics

Alternative Names: Adlea; ALGRX-4975; CNTX-4975; VLNX-4975

Latest Information Update: 27 Apr 2017

Price : $50

At a glance

  • Originator Johns Hopkins University
  • Developer Anesiva; Centrexion Therapeutics
  • Class Antipruritics; Catechols; Local anaesthetics; Monounsaturated fatty acids; Non-opioid analgesics; Polyunsaturated alkamides; Small molecules
  • Mechanism of Action Substance P inhibitors; TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neuropathic pain
  • New Molecular Entity No

Highest Development Phases

  • Phase II Neuropathic pain; Pain
  • Discontinued Postoperative pain

Most Recent Events

  • 16 Mar 2017 Efficacy data from a phase IIb trial in Post-operative pain (osteoarthritis) released by Centrexion Therapeutics
  • 01 Mar 2017 Centrexion completes a phase II extension trial in Pain in USA (NCT02678793)
  • 01 Feb 2017 Centrexion Therapeutics completes a phase II trial in Pain (In adults, In the elderly) in USA (Intra-articular) (NCT02558439)
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