Drug Profile


Alternative Names: ABT 578; Endeavor; Endeavor Resolute; MDT-4107 DES; Resolute DES; Resolute Onyx; ZoMaxx; Zotarolimus-eluting coronary stent system

Latest Information Update: 04 Nov 2016

Price : $50

At a glance

  • Originator Abbott Laboratories
  • Developer Medtronic
  • Class Ischaemic heart disorder therapies; Lactones; Macrolides; Polyenes; Tetrazoles
  • Mechanism of Action MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Coronary artery restenosis
  • No development reported Erectile dysfunction
  • Discontinued Vascular restenosis

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for phase-I development in Erectile-dysfunction in USA (Intra-arterial, Implant)
  • 31 May 2016 Medtronic completes the RESOLUTE US trial for Coronary artery restenosis (NCT00726453)
  • 01 Dec 2015 Medtronic completes a phase III trial in Coronary artery restenosis in China (Intracoronary) (NCT02452736)
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