Drug Profile


Alternative Names: ABT 578; Endeavor; Endeavor Resolute; MDT-4107 DES; Resolute DES; Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System (34/38 mm); Resolute Onyx; ZoMaxx; Zotarolimus-eluting coronary stent system

Latest Information Update: 21 Aug 2017

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At a glance

  • Originator Abbott Laboratories
  • Developer Medtronic
  • Class Ischaemic heart disorder therapies; Lactones; Macrolides; Polyenes; Tetrazoles
  • Mechanism of Action MTOR protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Coronary artery restenosis
  • No development reported Erectile dysfunction
  • Discontinued Vascular restenosis

Most Recent Events

  • 14 Aug 2017 Medtronic initiates the RESOLUTE ONYX ONE-MONTH DAPT trial in patients with Coronary artery restenosis
  • 17 Apr 2017 Medtronic initiates enrolment in a clinical trial for Coronary artery restenosis in China (NCT03118531)
  • 16 Jul 2016 No recent reports of development identified for phase-I development in Erectile-dysfunction in USA (Intra-arterial, Implant)
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