AZD 5363

Drug Profile

AZD 5363

Alternative Names: AZD-5363

Latest Information Update: 13 Oct 2017

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At a glance

  • Originator Astex Therapeutics; Cancer Research Technology; The Institute of Cancer Research
  • Developer Astex Therapeutics; AstraZeneca; Cancer Research Technology; Conquer Cancer Foundation; Netherlands Cancer Institute; Royal Marsden NHS Foundation Trust; Samsung Medical Center; The Institute of Cancer Research; University of Nottingham; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Proto oncogene protein c-akt inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer; Colorectal cancer; Gastric cancer; Non-small cell lung cancer; Prostate cancer
  • Phase I/II Fallopian tube cancer; Ovarian cancer; Peritoneal cancer; Solid tumours

Most Recent Events

  • 12 Sep 2017 Safety and efficacy data from the phase-I/II BEECH trial in Breast cancer presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017)
  • 12 Sep 2017 Safety and efficacy data from a phase-I/II clinical trial in Breast cancer, Fallopian tube cancer, Ovarian cancer and Peritoneal cancer presented at the 42nd European Society for Medical Oncology Congress (ESMO-2017)
  • 17 Jun 2017 Institute of Cancer Research completes a phase II trial in Prostate cancer (Metastatic disease, Combination therapy, Second-line therapy or greater, Late-stage disease) in United Kingdom (PO) (ISRCTN17168679)
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