Bis-choline tetrathiomolybdate - Wilson Therapeutics

Drug Profile

Bis-choline tetrathiomolybdate - Wilson Therapeutics

Alternative Names: ATN-224; Decuprate; WTX-101

Latest Information Update: 15 Nov 2017

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At a glance

  • Originator Attenuon LLC
  • Developer Attenuon; Cancer Research UK; Wilson Therapeutics
  • Class Antineoplastics; Heavy metals; Neuroprotectants; Small molecules
  • Mechanism of Action Chelating agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hepatolenticular degeneration
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatolenticular degeneration
  • Discontinued Breast cancer; Malignant melanoma; Multiple myeloma; Prostate cancer; Solid tumours

Most Recent Events

  • 20 Oct 2017 Interim pharmacodynamics, adverse events and efficacy data from a phase II trial in Wilson's disease presented at the 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2017)
  • 20 Oct 2017 Preclinical trials in Wilson's disease in Sweden (IV)
  • 20 Oct 2017 Pharmacokinetics data from a preclinical study in Wilson's disease presented at the 68th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2017)
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