Ustekinumab

Drug Profile

Ustekinumab

Alternative Names: Anti-IL-12/23p40 monoclonal antibody; Anti-interleukin-12 p40 monoclonal antibody; CNTO-1275; STELARA; Stelara

Latest Information Update: 05 Jan 2017

Price : $50

At a glance

  • Originator Centocor; Medarex
  • Developer Centocor; Janssen Biotech; Janssen Pharmaceutical KK; Janssen-Cilag
  • Class Antipsoriatics; Monoclonal antibodies
  • Mechanism of Action Immunosuppressants; Interleukin 12 subunit p40 inhibitors; Interleukin 23 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Plaque psoriasis; Psoriatic arthritis
  • Registered Crohn's disease
  • Phase III Spondylarthritis; Ulcerative colitis
  • Phase II Atopic dermatitis; Systemic lupus erythematosus
  • Phase I Inflammation
  • Discontinued Multiple sclerosis; Palmoplantar pustulosis; Primary biliary cirrhosis; Rheumatoid arthritis; Sarcoidosis

Most Recent Events

  • 16 Dec 2016 Preregistration for Plaque psoriasis (In adolescents) in USA (SC)
  • 14 Dec 2016 Registered for Crohn's disease (Treatment-experienced) in Canada (SC)
  • 14 Dec 2016 Registered for Crohn's disease (Treatment-experienced) in Canada (IV)
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