Drug Profile


Alternative Names: Anti-interleukin-12 p40 monoclonal antibody; CNTO-1275; STELARA; Stelara; Stellara; Sterrara; Suterara

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Centocor; Medarex
  • Developer Centocor; Janssen Biotech; Janssen Pharmaceutical KK; Janssen Research & Development; Janssen-Cilag
  • Class Antipsoriatics; Monoclonal antibodies
  • Mechanism of Action Immunosuppressants; Interleukin 12 subunit p40 inhibitors; Interleukin 23 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Crohn's disease; Plaque psoriasis; Psoriatic arthritis
  • Phase III Spondylarthritis; Ulcerative colitis
  • Phase II Atopic dermatitis; Systemic lupus erythematosus
  • Phase I Inflammation
  • Discontinued Multiple sclerosis; Palmoplantar pustulosis; Primary biliary cirrhosis; Rheumatoid arthritis; Sarcoidosis

Most Recent Events

  • 14 Jul 2017 The UK's NICE recommends ustekinumab for Plaque psoriasis (In adolescents)
  • 24 May 2017 Launched for Crohn's disease in Japan (IV)
  • 19 Apr 2017 Janssen initiates enrolment in a phase III trial for Crohn's disease in United Kingdom and Belgium (NCT03107793)
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