Drug Profile


Alternative Names: DHPS; GSK-2894512; WBI-1001

Latest Information Update: 31 Jul 2017

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At a glance

  • Originator Welichem Biotech
  • Developer Beijing Wenfeng Tianji Pharmaceuticals; Celestial Pharmaceuticals; Stiefel Laboratories; Welichem Biotech
  • Class Nonsteroidal anti-inflammatories; Resorcinols; Small molecules; Stilbenes
  • Mechanism of Action Cell movement inhibitors; Cytokine inhibitors; Phosphotransferase inhibitors; T lymphocyte inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Psoriasis
  • Phase II Atopic dermatitis; Plaque psoriasis
  • Preclinical Inflammatory bowel diseases

Most Recent Events

  • 30 Jun 2017 GlaxoSmithKline plans a phase I trial for Psoriasis (In volunteers) (NCT03201978)
  • 30 Jun 2017 GlaxoSmithKline plans a phase III trial for Plaque psoriasis (NCT03202004)
  • 13 Jun 2017 Phase-II clinical trials in Atopic dermatitis in China (Topical) (ChiCTR-IIR17012153)
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