Drug Profile


Alternative Names: CLS-003; Furosemide/digoxin; ICVT; Ionic contra viral therapy

Latest Information Update: 14 Nov 2017

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At a glance

  • Originator Henderson Morley
  • Developer Cutanea Life Sciences; Henderson Morley
  • Class Antihypertensives; Antivirals; Glycosides; Skin disorder therapies; Small molecules; Sulfanilamides
  • Mechanism of Action Potassium channel antagonists; Virus replication inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Recurrent respiratory papillomatosis
  • New Molecular Entity No

Highest Development Phases

  • Phase II Genital warts; Vulvar intraepithelial neoplasia
  • Discontinued Herpes simplex virus infections; Human papillomavirus infections; Infectious keratoconjunctivitis

Most Recent Events

  • 05 Oct 2017 Phase-II clinical trials in Vulvar intraepithelial neoplasia in Netherlands (Topical) (NCT03334240)
  • 05 Oct 2017 Cutanea Life Sciences initiates enrolment in a phase II trial for Genital warts in Netherlands (Topical) (NCT03334240)
  • 07 Feb 2017 Phase-II development is ongoing in Netherlands (Topical)
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