Research programme: A3 adenosine receptor agonists - Can-Fite BioPharma

Drug Profile

Research programme: A3 adenosine receptor agonists - Can-Fite BioPharma

Alternative Names: A3 adenosine receptor allosteric modulators - Can-Fite BioPharma; CF 402; CF-402 - Can-Fite BioPharma; CF-502; CF-602

Latest Information Update: 25 Sep 2017

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At a glance

  • Originator Can-Fite BioPharma; Leiden University; National Institutes of Health (USA)
  • Developer Can-Fite BioPharma
  • Class Amides; Anti-inflammatories; Cyclohexanes; Quinolines; Small molecules
  • Mechanism of Action Adenosine A3 receptor agonists; Nitric oxide stimulants; Vascular endothelial growth factors stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Autoimmune disorders; Inflammation; Sexual function disorders

Most Recent Events

  • 18 Sep 2017 Can-Fite BioPharma files for patent protection of its drugs and other ligands which target the A3 adenosine receptor to treat Cytokine release syndrome
  • 31 Dec 2016 Can-Fite BioPharm receives patent for A3 adenosine receptor (A3AR) agonists in USA
  • 09 Nov 2016 Can-Fite BioPharm receives patent allowance for CF 602 in USA
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