Bosutinib

Drug Profile

Bosutinib

Alternative Names: Bosulif; PF-05208763; PF-5208763; SKI-606

Latest Information Update: 15 Jul 2017

Price : $50

At a glance

  • Originator Wyeth
  • Developer Avillion; Massachusetts General Hospital; Pfizer; University of Texas M. D. Anderson Cancer Center
  • Class Aniline compounds; Antineoplastics; Nitriles; Piperazines; Quinolines; Small molecules
  • Mechanism of Action Bcr-abl tyrosine kinase inhibitors; Src-Family kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Chronic myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Chronic myeloid leukaemia
  • Phase II Glioblastoma
  • Phase I/II Acute lymphoblastic leukaemia
  • Discontinued Autosomal dominant polycystic kidney disease; Breast cancer; Solid tumours

Most Recent Events

  • 06 Jun 2017 Initial efficacy and adverse events data from a phase III trial in Chronic myeloid leukaemia presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 15 May 2017 Phase-II clinical trials in Chronic myeloid leukaemia (Newly diagnosed, Monotherapy) in Japan (PO) (NCT03128411)
  • 28 Apr 2017 Pfizer plans a phase II trial for Chronic myeloid leukaemia (Newly diagnosed, Monotherapy) (NCT03128411)
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