Drug Profile


Alternative Names: Chlorpromazine/pentamidine; CRx-026

Latest Information Update: 23 Sep 2010

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At a glance

  • Originator CombinatoRx
  • Developer Zalicus
  • Class Antiemetics; Antineoplastics; Antiprotozoals; Antipsychotics; Benzamidines; Phenothiazines
  • Mechanism of Action Apoptosis stimulants; KIF11 protein inhibitors; Mitosis inhibitors; Phosphoric monoester hydrolase inhibitors; Protein-tyrosine-phosphatase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 25 May 2007 CombinatoRx completes two phase I/II trials in late-stage or metastatic Solid tumours in the US
  • 21 Jul 2005 Pentamidine/chlorpromazine has been licensed to HenKan in Taiwan, China and South Korea
  • 20 Jul 2005 This programme is still in active development
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