SG 2000

Drug Profile

SG 2000

Alternative Names: BN-2629; NCI 694501; NSC 694501; Project P011; SJG-136; SP 2001; UP-2001

Latest Information Update: 03 Dec 2015

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At a glance

  • Originator Spirogen
  • Developer National Cancer Institute (USA); Spirogen
  • Class Benzodiazepines; Cytostatic antibiotics; Pyrroles
  • Mechanism of Action DNA cross linking agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia; Chronic lymphocytic leukaemia
  • Discontinued Fallopian tube cancer; Ovarian cancer; Peritoneal cancer

Most Recent Events

  • 03 Dec 2015 Spirogen terminates a phase I/II trial for Chronic lymphocytic leukaemia and Acute myeloid leukaemia (Second-line therapy or greater, Late stage disease) in USA (NCT02034227)
  • 15 Oct 2013 Spirogen has been acquired by MedImmune
  • 31 Jul 2013 The National Cancer Institute terminates a phase II trial in Ovarian cancer, Peritoneal cancer & Fallopian tube cancer in USA (NCT01200797)
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