Blinatumomab

Drug Profile

Blinatumomab

Alternative Names: AMG-103; Blincyto; MEDI-538; MT-103

Latest Information Update: 17 Feb 2017

Price : $50

At a glance

  • Originator Micromet Inc
  • Developer Amgen; Astellas Pharma; M. D. Anderson Cancer Center; Micromet Inc; National Cancer Institute (USA)
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action Immunostimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mantle-cell lymphoma; B cell prolymphocytic leukaemia; Acute lymphoblastic leukaemia; B cell lymphoma; T cell prolymphocytic leukaemia; Chronic lymphocytic leukaemia; Hairy cell leukaemia
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute lymphoblastic leukaemia
  • Phase II/III Non-Hodgkin's lymphoma
  • Phase II Diffuse large B cell lymphoma
  • Discontinued Chronic lymphocytic leukaemia

Most Recent Events

  • 14 Feb 2017 Amgen files sBLA for Ph+ B-cell precursor Acute lymphoblastic leukaemia (Second-line therapy or greater) in USA
  • 11 Jan 2017 Phase-II clinical trials in Diffuse large B cell lymphoma (Newly diagnosed, Adjunctive treatment) in Spain (IV) (EudraCT2016-002190-35)
  • 01 Jan 2017 Phase-II/III clinical trials in Non-Hodgkin's lymphoma (Monotherapy, Second-line therapy or greater) in USA, Belgium, Australia, United Kingdom, Spain (IV) (NCT02910063)
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