Tofacitinib

Drug Profile

Tofacitinib

Alternative Names: Cp-690-550; CP-690550; Jaquinus; Tasocitinib; Tofacitinib citrate; Xeljanz; Xeljanz XR

Latest Information Update: 07 Aug 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Pfizer
  • Developer Johns Hopkins University; Pfizer
  • Class 2 ring heterocyclic compounds; Amides; Nitriles; Piperidines; Pyrimidines; Pyrroles; Small molecules
  • Mechanism of Action Immunosuppressants; Janus kinase 1 inhibitors; Janus kinase 3 inhibitors; Janus kinase-2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Rheumatoid arthritis
  • Preregistration Psoriatic arthritis; Ulcerative colitis
  • Phase III Juvenile rheumatoid arthritis; Plaque psoriasis
  • Phase II Atopic dermatitis
  • Phase I Dermatomyositis
  • Discontinued Ankylosing spondylitis; Asthma; Crohn's disease; Dry eyes; Irritable bowel syndrome; Renal transplant rejection

Most Recent Events

  • 03 Aug 2017 The US FDA Arthritis Advisory Committee recommends sNDA approval of tofacitinib 5mg bid and tofacitinib extended release 11mg od in Psoriatic arthritis
  • 13 Jul 2017 Preregistration for Ulcerative colitis in USA (PO)
  • 13 Jul 2017 FDA provides an anticipated PDUFA action date of March 2018 for tofacitinib for Ulcerative colitis
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top