PPL 100

Drug Profile

PPL 100

Alternative Names: MK-8122; PL-100; PPL-100; TMB-607

Latest Information Update: 17 Apr 2017

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At a glance

  • Originator Ambrilia Biopharma
  • Developer Ambrilia Biopharma; TaiMed Biologics; Temple University
  • Class Aniline compounds; Antiretrovirals; Benzhydryl compounds; Carbamates; Phosphoric acid esters; Small molecules; Sulfonamides
  • Mechanism of Action HIV protease inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I HIV infections

Most Recent Events

  • 21 Nov 2016 Phase-I clinical trials in HIV infections (In volunteers) in USA (IM) (NCT03110549)
  • 21 Nov 2016 Phase-I clinical trials in HIV infections (In volunteers) in USA (SC) (NCT03110549)
  • 20 May 2016 PPl 100 (SC, IM) is still in preclinical development for HIV infections in Taiwan
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