Ocrelizumab

Drug Profile

Ocrelizumab

Alternative Names: 2nd Generation Anti-CD20; Anti-CD20 monoclonal antibody - Biogen; Humanised Anti-CD20 mAb; OCR; Ocrevus; PRO 70769; R 1594; RG 1594; rhuMab 2H7; RO4964913

Latest Information Update: 09 Jun 2017

Price : $50

At a glance

  • Originator Biogen Idec; Genentech
  • Developer Biogen; Biogen Idec; Chugai Pharmaceutical; Genentech; Roche
  • Class Monoclonal antibodies
  • Mechanism of Action B cell inhibitors; CD20 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Multiple sclerosis
  • Discontinued Eye disorders; Haematological malignancies; Lupus nephritis; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 26 Apr 2017 Additional efficacy data from the phase III OPERA I and OPERA II trial in Multiple sclerosis released by Genentech
  • 22 Apr 2017 Long term efficacy data from the phase II OPERA-II trail in Multiple sclerosis presented at the 69th Annual Meeting of the American Academy of Neurology (AAAN-2017)
  • 31 Mar 2017 Discontinued - Phase-III for Systemic lupus erythematosus in Thailand, South Africa, Singapore, Philippines, Malaysia, Latin America, European Union, Canada, USA (IV)
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