Drug Profile


Alternative Names: 2nd Generation Anti-CD20; Anti-CD20 monoclonal antibody - Biogen; Humanised Anti-CD20 mAb; OCR; Ocrevus; PRO 70769; R 1594; RG 1594; rhuMab 2H7; RO4964913

Latest Information Update: 31 Mar 2017

Price : $50

At a glance

  • Originator Biogen Idec; Genentech
  • Developer Biogen; Biogen Idec; Chugai Pharmaceutical; Genentech; Roche
  • Class Monoclonal antibodies
  • Mechanism of Action B cell inhibitors; CD20 antigen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Registered Multiple sclerosis
  • Discontinued Eye disorders; Haematological malignancies; Lupus nephritis; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 31 Mar 2017 Discontinued - Phase-III for Systemic lupus erythematosus in Thailand, South Africa, Singapore, Philippines, Malaysia, Latin America, European Union, Canada, USA (IV)
  • 28 Mar 2017 Registered for Multiple sclerosis in USA (IV) - First global approval
  • 22 Mar 2017 Roche initiates enrolment in a phase III trial for Multiple sclerosis (Relapsing-remitting) in USA and Australia (NCT03085810)
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