Drug Profile


Alternative Names: Avalide; Avapro HCT; CoAprovel; Karvezide

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator sanofi-aventis
  • Class Antihypertensives; Benzothiadiazines; Biphenyl compounds; Tetrazoles
  • Mechanism of Action Angiotensin type 1 receptor antagonists; Diuretics
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Diabetic nephropathies; Hypertension

Most Recent Events

  • 31 Mar 2015 Launched for Hypertension in Algeria, Morocco and Philippines (PO) before March 2015
  • 03 Oct 2012 Bristol-Myers Squibb intends to terminate its licence for irbesartan/hydrochlorothiazide in all countries, effective 1 January 2013
  • 04 Apr 2012 First generic version of irbesartan hydrochlorothiazide launched in the USA
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