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Drug Profile

Afimoxifene - BHR Pharma

Alternative Names: 4-Hydroxytamoxifen; 4-Hydroxytamoxifen (afimoxifene) gel; 4-Hydroxytamoxifen gel; 4-OH tamoxifen; 4-OHT; TamoGel

Latest Information Update: 11 Dec 2024

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At a glance

  • Originator Besins International
  • Developer Besins Healthcare; BHR Pharma
  • Class Antineoplastics; Hydroxytestosterones; Non-opioid analgesics
  • Mechanism of Action Estrogen receptor antagonists; Selective estrogen receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Breast cancer
  • No development reported Breast pain; Gynaecomastia
  • Discontinued Hyperplasia; Keloids

Most Recent Events

  • 11 Dec 2024 Discontinued - Phase-III for Hyperplasia in Germany, Spain, USA (Topical) (BHR Pharma pipeline, December 2024)
  • 08 Mar 2022 No development reported - Phase-III for Hyperplasia in Spain, Germany, USA (Topical)
  • 24 Jan 2022 National Cancer Institute in collaboration with Northwestern University completes a phase IIb trial in Breast cancer in USA (Topical) (NCT02993159)

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