Emtricitabine/tenofovir disoproxil fumarate

Drug Profile

Emtricitabine/tenofovir disoproxil fumarate

Alternative Names: Emtriva®/Viread®; F/TDF; FTC/TDF; TDF/FTC; Tenofovir disoproxil fumarate/emtricitabine; Truvada; TVD; Viread®/Emtriva®

Latest Information Update: 21 Sep 2017

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At a glance

  • Originator Gilead Sciences
  • Developer Gador; Gilead Sciences; Japan Tobacco; National Institute of Allergy and Infectious Diseases; Stendhal Mexico; University of Alberta; University of Washington
  • Class Antiretrovirals; Deoxyribonucleosides; Nucleotides; Phosphonic acids; Purines; Pyrimidine nucleosides
  • Mechanism of Action Nucleoside reverse transcriptase inhibitors; Nucleotide reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed HIV infections
  • Phase III Hepatitis B
  • Phase II Primary biliary cirrhosis

Most Recent Events

  • 21 Sep 2017 International Partnership for Microbicides and Gilead Sciences withdraws the phase II REACH study for HIV-1 infection (Prevention, In volunteers, In adolescent, In adult) in South Africa prior to enrolment, as it was transferred to partner who will conduct under its own IND (NCT03074786)
  • 14 Mar 2017 International Partnership for Microbicides and Gilead Sciences plan the REACH phase II trial for HIV infection (Prevention, In volunteers, Combination therapy) in South Africa (NCT03074786)
  • 27 Feb 2017 Gilead Sciences has patent protection for emtricitabine/tenofovir disoproxil fumarate in USA and European Union (Gilead Sciences 10-K, February 2017)
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