Drug Profile


Alternative Names: ACT-GRO-777; AGRO-100; AS1411

Latest Information Update: 16 Jul 2016

Price : *
* Final gross price and currency may vary according to local VAT and billing address.

At a glance

  • Originator University of Alabama; University of Louisville
  • Developer Advanced Cancer Therapeutics; James Graham Brown Cancer Center
  • Class Antineoplastics; Nucleotide aptamers; Oligodeoxyribonucleotides
  • Mechanism of Action Apoptosis stimulants; Nucleolin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer; Acute myeloid leukaemia; Renal cell carcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cancer
  • No development reported Neuroblastoma

Most Recent Events

  • 16 Jul 2016 No recent reports of development identified for preclinical development in Neuroblastoma in USA (IV)
  • 03 May 2011 Preclinical trials in Neuroblastoma in USA (IV)
  • 28 Apr 2011 Advanced Cancer Therapeutics acquires ACT GRO 777 from Antisoma
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top