Drug Profile


Alternative Names: Anti-CD3 anti-EpCAM monoclonal antibody; Anti-CD3 X anti-EpCAM; Removab

Latest Information Update: 19 Mar 2015

Price : $50

At a glance

  • Originator TRION Pharma
  • Developer Neovii Biotech; Swedish Orphan Biovitrum; TRION Pharma
  • Class Antineoplastics; Bispecific antibodies; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Immunostimulants; Macrophage stimulants; Natural killer cell stimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer; Ovarian cancer
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Marketed Malignant ascites
  • Phase II Gastric cancer; Ovarian cancer
  • Phase I Carcinoma

Most Recent Events

  • 10 Mar 2015 Catumaxomab is still in phase II trials for Ovarian cancer in the USA, Austria, Germany and Spain
  • 09 Mar 2015 No recent reports on development identified - Phase-II for Malignant ascites (Recurrent) in USA (Intraperitoneal)
  • 19 Feb 2015 Neovii Biotech completes a phase II trial in Ovarian cancer in Spain (EudraCT2010-018478-19; NCT01246440) before February 2015
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