Tripterygium wilfordii Hook F extract - Phytomedics

Drug Profile

Tripterygium wilfordii Hook F extract - Phytomedics

Alternative Names: PMI-001; TwHF extract

Latest Information Update: 17 Aug 2015

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At a glance

  • Originator Phytomedics
  • Class Anti-inflammatories; Antirheumatics; Herbal medicines; Traditional-Chinese-medicine
  • Mechanism of Action Cyclo-oxygenase 2 inhibitors; Interleukin 2 inhibitors; Nitric oxide synthase type II inhibitors; Tumour necrosis factor alpha inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Rheumatoid arthritis

Most Recent Events

  • 11 Nov 2010 Phytomedics receives grant under the Qualifying Therapeutic Discovery Project Program for development of PMI 001 in Rheumatoid arthritis
  • 21 Aug 2009 Clinical development is ongoing in USA
  • 19 Aug 2009 Final efficacy and adverse events data from a phase II trial in Rheumatoid arthritis released by Phytomedics
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