Drug Profile


Alternative Names: PRX-00023

Latest Information Update: 19 Oct 2017

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At a glance

  • Originator EPIX Pharmaceuticals
  • Developer EPIX Pharmaceuticals; National Institute of Neurological Disorders and Stroke; Proximagen
  • Class Antidepressants; Anxiolytics; Piperazines; Small molecules; Sulfonamides
  • Mechanism of Action Serotonin 1A receptor agonists; Sigma-1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Epilepsy
  • Discontinued Drug-induced dyskinesia; Generalised anxiety disorder; Major depressive disorder

Most Recent Events

  • 06 Oct 2017 National Institute of Neurological Disorders and Stroke terminates phase II trial in Epilepsy in USA (NCT01281956)
  • 14 Aug 2012 Proximagen has been acquired by Upsher-Smith
  • 05 Mar 2012 Discontinued - Phase-I for Drug-induced dyskinesia in USA (PO)
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