Drug Profile


Alternative Names: PG545

Latest Information Update: 16 Oct 2017

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At a glance

  • Originator Progen Pharmaceuticals
  • Developer Medigen Biotechnology Corporation; Progen Pharmaceuticals Limited; TBG Diagnostics Limited
  • Class Antineoplastics; Glycosaminoglycans; Oligosaccharides; Small molecules
  • Mechanism of Action Dendritic cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Hepatocellular carcinoma
  • Discontinued Breast cancer; Ovarian cancer

Most Recent Events

  • 13 Jun 2017 Adverse events, pharmacokinetics and pharmacodynamics data from a phase I trial in Solid tumours presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 22 Sep 2016 Progen Pharmaceuticals completes a phase I trial in Solid tumours in Australia (NCT02042781)
  • 21 Jan 2014 Phase-I clinical trials in Solid tumours (late-stage disease) in Australia (IV)
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