Research programme: selective estrogen receptor modulators - SRI International

Drug Profile

Research programme: selective estrogen receptor modulators - SRI International

Alternative Names: NSC-732011; SR16158; SR16388

Latest Information Update: 03 Feb 2011

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At a glance

  • Originator SRI International
  • Class
  • Mechanism of Action Estrogen receptor antagonists; Hypoxia-inducible factor 1 inhibitors; Selective estrogen receptor modulators; STAT3 transcription factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Preclinical Colorectal cancer; Multiple myeloma; Non-small cell lung cancer; Prostate cancer

Most Recent Events

  • 11 May 2010 Preclinical trials in Multiple myeloma in USA (PO)
  • 11 May 2010 Interim pharmacodynamics data from a preclinical trial in Multiple myeloma released by SRI International
  • 25 Jan 2010 Preclinical development is ongoing the US (
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