CX 717

Drug Profile

CX 717

Alternative Names: Ampakine® CX717; CX717

Latest Information Update: 22 Jun 2017

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At a glance

  • Originator Cortex Pharmaceuticals
  • Developer Cortex Pharmaceuticals; National Institute on Drug Abuse; RespireRx Pharmaceuticals
  • Class Antidementias
  • Mechanism of Action AMPA receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Spinal cord injuries
  • Preclinical Drug abuse
  • Discontinued Alzheimer's disease; Attention-deficit hyperactivity disorder; Respiratory insufficiency; Sleep disorders

Most Recent Events

  • 14 Jun 2017 Phase-I clinical trials in Spinal cord injuries (unspecified route) before June 2017 (RespireRx Pipeline, June 2017)
  • 14 Jun 2017 RespireRx plans to file an IND, and initiate a phase II trial investigating the ability of CX 717 to improve breathing in patients with spinal cord injury, during 2017
  • 19 Jan 2016 RespireRx Pharmaceuticals and NIDA agree to co-develop CX 717 in USA for Drug abuse
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