Drug Profile


Alternative Names: ALT 110; Brain cancer vaccine - Celldex Therapeutics; CDX-110; PF-04948568; PF-04948569; PF-4948568; PF-4948569; Rindo; Rintega; SPX 110

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Duke University; Johns Hopkins University
  • Developer Celldex Therapeutics Inc
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action Epidermal growth factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Glioblastoma; Solid tumours

Most Recent Events

  • 08 Aug 2016 Discontinued - Phase-I for Solid tumours in USA (Intradermal)
  • 08 Aug 2016 Discontinued - Phase-II for Glioblastoma (Combination therapy, Second-line therapy or greater) in USA (Intradermal)
  • 08 Aug 2016 Discontinued - Phase-III for Glioblastoma (First-line therapy) in Australia, Canada, India, Czech Republic, Mexico, New Zealand, Taiwan, Thailand, Austria, Belgium, France, Germany, Greece, Israel, Netherlands, Spain, Switzerland, Brazil, Colombia, Hungary, Peru, United Kingdom, Italy and USA (Intradermal)
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