ONX 0801

Drug Profile

ONX 0801

Alternative Names: BGC 945; BTG-945

Latest Information Update: 08 Jul 2017

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At a glance

  • Originator BTG; The Institute of Cancer Research
  • Developer Onyx Pharmaceuticals; Royal Marsden NHS Foundation Trust; The Institute of Cancer Research
  • Class Antineoplastics; Quinazolines
  • Mechanism of Action Thymidylate synthase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 06 Jun 2017 Efficacy and safety data from a phase I trial in Solid tumours released by The Institute of Cancer Research
  • 02 Jun 2017 Pharmacokinetics and efficacy data from a phase-I trial in Solid tumours presented at the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO-2017)
  • 11 Mar 2016 Phase-I development is ongoing in United Kingdom
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