Vorsetuzumab mafodotin

Drug Profile

Vorsetuzumab mafodotin

Alternative Names: SGN-75

Latest Information Update: 17 Mar 2014

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At a glance

  • Originator Seattle Genetics
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Non-Hodgkin's lymphoma; Renal cancer

Most Recent Events

  • 31 Dec 2013 Seattle Genetics terminates phase I trial in Renal cancer (combination therapy) in USA (NCT01677390)
  • 06 Nov 2013 Discontinued - Phase-I for Non-Hodgkin's lymphoma in USA (IV)
  • 06 Nov 2013 Discontinued - Phase-I for Renal cancer in USA (IV)
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