Tenofovir exalidex - ContraVir Pharmaceuticals

Drug Profile

Tenofovir exalidex - ContraVir Pharmaceuticals

Alternative Names: CMX-157; HDP-Tenofovir; Hexadecyloxypropyl-tenofovir; lipid conjugate TFV(tenofovir); Lipid conjugate YTFV; TXL™

Latest Information Update: 19 Sep 2017

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At a glance

  • Originator Chimerix
  • Developer Chimerix; ContraVir Pharmaceuticals
  • Class Antiretrovirals; Phosphonic acids; Purines; Small molecules
  • Mechanism of Action Nucleotide reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Hepatitis B
  • Suspended HIV infections

Most Recent Events

  • 11 Sep 2017 The US FDA approves IND application for tenofovir exalidex in Hepatitis B
  • 11 Sep 2017 ContraVir Pharmaceuticals plans a phase I clinical trial for Renal impairment in September 2017
  • 06 Sep 2017 Phase-I clinical trials in Hepatitis B treatment (In volunteers) in United Kingdom (PO) (NCT03279146)
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