Tenofovir exalidex

Drug Profile

Tenofovir exalidex

Alternative Names: CMX 157; HDP-Tenofovir; Hexadecyloxypropyl-tenofovir; TXL

Latest Information Update: 23 Feb 2017

Price : $50

At a glance

  • Originator Chimerix
  • Developer Chimerix; ContraVir Pharmaceuticals
  • Class Antiretrovirals; Phosphonic acids; Purines; Small molecules
  • Mechanism of Action RNA-directed DNA polymerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Hepatitis B
  • Suspended HIV infections

Most Recent Events

  • 11 Nov 2016 Updated safety and pharmacokinetics data from a phase I trial (Healthy volunteers) and phase Ib/IIa trial in Hepatitis B presented at The Liver Meeting® 2016: 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2016)
  • 13 Oct 2016 Positive interim efficacy,safety and pharmacokinetic data from a phase Ib/IIa trial in hepatitis B released by ContraVir Pharmaceuticals
  • 12 Sep 2016 New pharmacodynamics data from preclinical study presented at The Liver Meeting® 2016: 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2016) and The International Liver Congress™ 2016 (ILC-2016)
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