Lofexidine

Drug Profile

Lofexidine

Alternative Names: BA-168; BritLofex; Lofexidine hydrochloride; MDL-14042; MDL-14042A; RMI-14042A

Latest Information Update: 07 Sep 2017

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At a glance

  • Originator Britannia Pharmaceuticals
  • Developer Britannia Pharmaceuticals; National Institute on Drug Abuse; US WorldMeds
  • Class Antihypertensives; Chlorobenzenes; Imidazolines; Phenyl ethers; Small molecules
  • Mechanism of Action Alpha 2 adrenergic receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes - Opioid abuse

Highest Development Phases

  • Marketed Opioid abuse

Most Recent Events

  • 05 Sep 2017 US WorldMeds enters into a manufacturing agreement with Catalent Pharma Solutions
  • 05 Sep 2017 Lofexidine receives Fast Track designation for Opioid abuse [PO,Tablet] in USA
  • 01 Jun 2016 US WorldMeds initiates a phase I pharmacokinetic trial for Opioid abuse in USA (NCT02801357)
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