Nelipepimut S

Drug Profile

Nelipepimut S

Alternative Names: Cancer vaccine E75; Cancer vaccine E75 - Apthera; Cancer vaccine Her2/neu E75 - Apthera; E75; E75 peptide; E75/GM-CSF vaccine; Nelipepimut-S; NeuVax

Latest Information Update: 28 Jul 2017

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At a glance

  • Originator Henry M. Jackson Foundation for the Advancement of Military Medicine; Uniformed Services University of the Health Sciences; University of Texas M. D. Anderson Cancer Center
  • Developer Galena Biopharma; University of Texas M. D. Anderson Cancer Center
  • Class Cancer vaccines; Peptide vaccines; Peptides
  • Mechanism of Action CD8 positive T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes - Cancer

Highest Development Phases

  • Phase III Breast cancer
  • Phase I Gastric cancer
  • Preclinical Bladder cancer; Ovarian cancer; Pancreatic cancer
  • Discontinued Prostate cancer

Most Recent Events

  • 12 Jul 2017 Nelipepimut S is available for licensing as of 12 Jul 2017.
  • 04 Apr 2017 Adverse events data from a phase II trial in Breast cancer presented at the American Association for Cancer Research-2017 (AACR-2017)
  • 30 Nov 2016 Galena Biopharma resumes enrolment a phase II trial in Breast cancer (Neoadjuvant therapy, Combination therapy) in USA (Intradermal) (NCT02636582)
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