Drug Profile


Alternative Names: CP-675; CP-675,206; Ticilimumab

Latest Information Update: 13 Jan 2017

Price : $50

At a glance

  • Originator Pfizer
  • Developer Amgen; AstraZeneca; Azienda Ospedaliera Universitaria Senese; Canadian Cancer Trials Group; Immunocore; M. D. Anderson Cancer Center; MedImmune; Memorial Sloan-Kettering Cancer Center; National Cancer Institute (USA); Northwestern University; Pfizer
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Cytotoxic T-lymphocyte antigen 4 inhibitors; Interleukin 2 stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mesothelioma
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Head and neck cancer; Mesothelioma; Non-small cell lung cancer
  • Phase II Breast cancer; Endometrial cancer; Gastric cancer; Glioblastoma; Hepatocellular carcinoma; Pancreatic cancer; Prostate cancer; Sarcoma; Small cell lung cancer; Solid tumours
  • Phase I/II Malignant melanoma; Peritoneal cancer
  • Phase I Colorectal cancer; Diffuse large B cell lymphoma; Renal cell carcinoma
  • No development reported Gastrointestinal cancer; Urogenital cancer

Most Recent Events

  • 01 Jan 2017 Phase-II clinical trials in Endometrial cancer (Combination therapy, Second-line therapy or greater, Recurrent) in USA (IV) (NCT03015129)
  • 23 Dec 2016 City of Hope Medical Center plans a pilot trial in Colorectal cancer (Combination therapy) in USA (NCT03005002)
  • 15 Dec 2016 Breast International Group and UNICANCER plan the phase II ULTIMATE trial for Breast cancer (Combination therapy, Neoadjuvant therapy) in France (IV) (NCT02997995)
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